2015-10-01 · RIFM's Expert Panel is composed of scientific and technical experts in their respective fields. This group provides advice and guidance. 3. Information sources outside of RIFM's database are noted as appropriate in the safety assessment.
The RIFM Database is the most comprehensive, worldwide source of toxicology data, literature and general information on fragrance and flavor raw materials. Login to the RIFM Database Fragrance Material Safety Resource Center
Chances are you are exposed to at least a dozen products that contain fragrance on a daily basis. Unfortunately we are unknowingly being exposed to potentially hundreds of chemicals as a result, The RIFM database was established in 1983 as a means of maintaining up-to-date science-based information for businesses involved in the fragrance industry. It now contains key information on 5,000 fragrance and flavor materials, together with 53,000 references, containing over 111,000 human health and environmental studies. There are over 55,000 references and 5,000 materials in this database which is continuously evolving and expanding with the addition of new updated information.
The RIFM database was established in 1983 as a means of maintaining up-to-date science-based information for businesses involved in the fragrance industry. It now contains key information on 5,000 fragrance and flavor materials, together with 53,000 references, containing over 111,000 human health and environmental studies. The comprehensive RIFM database does exist, and is apparently full of interesting and pertinent data on the safety of fragrance chemicals. Unfortunately, one must be a dues paying member of IFRA to gain access to the database. Ethylene Brassylate safety assessment based on RIFM's criteria.
2020-06-17 · As members, doTERRA will have access to RIFM’s comprehensive database on fragrance and flavor ingredients, which provides upwards of 70,000 references that include more than 135,000 human health
2021-01-15 · Each endpoint discussed in this safety assessment includes the relevant data that were available at the time of writing (version number in the top box is indicative of the date of approval based on a 2-digit month/day/year), both in the RIFM Database (consisting of publicly available and proprietary data) and through publicly available information sources (e.g., SciFinder and PubMed). RIFM ID Principle/Main CAS RIFM DATABASE ALTERNATIVE/EINECS CAS NO Principle Name Botanical/Binomial name CAS No. IFRA Name/Principle Name Level (%) G2.12 8006-77-7 84929-57-7 Allspice oil Pimenta officinalis Lindl.
2015-10-01
RIFM number: 950 2. Physical data 1. Boiling point: 289.96 C [EPI Suite] 2. Flash point: >200 F; CC [FMA database] 3. Log KOW: 3.84 [EPI Suite] 4. Melting point: 23.28 C [EPI Suite] 5. Water solubility: 26.42 mg/L [EPI Suite] 6.
IFRA is informed, and may or may not implement risk management measures.
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Ethylene Brassylate safety assessment based on RIFM's criteria. • Safety assessment based on 7 Human health endpoints plus environmental. • All endpoints were cleared using data on the target material, read across and/or TTC. p-Isopropylbenzyl alcohol; a safety assessment based on RIFM's criteria.A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.
box is indicative of the date of approval based on a two digit month/day/year), both in the RIFM database (consisting of publicly available and proprietary data) and through publicly available information sources (i.e., SciFinder and PubMed).
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Obviously, a comprehensive review of this number of substances is a massive undertaking and requires a systematic and scientific approach both in determining the order in which they should be reviewed and in development of the necessary database for such a review. The general approach is based on the RIFM (Research Institute for Fragrance Materials, Inc.), 2009 Repeated insult patch test on melissa oil in humans.
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The RIFM database identified a total of 476 chemicals that were added to the existing TTC databases. The chemicals were then individually assigned a Cramer class and 238, 76 and 162 chemicals in Cramer class I, II and III respectively were identified.
The RIFM Database RIFM Fragrance Database Sheet Read more about the scientific and regulatory information that you can find on each ingredient in the RIFM Database. The RIFM Database is the most comprehensive, worldwide source of toxicology data, literature and general information on fragrance and flavor raw materials.
The RIFM Database of flavor and fragrance materials is the largest available in the world. RIFM Vice President Anne Marie Api, PhD, oversees RIFM’s research, including collaborative efforts to ensure that robust exposure data inform RIFM’s Safety Assessment Process.
97-53-0 Eugenol 93-15-2 Methyl eugenol G2.21 Allspice oleoresin Pimenta officinalis Lindl. H2.12 8013-76-1 90320-35-7 RIFM is listed in the World's largest and most authoritative dictionary database of and designed using information in the RIFM proprietary database 6. RIFM number: 950 2. Physical data 1. Boiling point: 289.96 C [EPI Suite] 2.
Specific gravity: 0.82500 @ 25.00 C1 7. Vaporpressure: 0.002mmHg20 C[FMAdatabase],0.00204mm date of approval based on a two digit month/day/year), both in the RIFM database (consisting of publicly available and proprietary data) and through publicly available information sources (i.e., SciFinder and PubMed). Studies selected for this safety assessment were based on appropriate test criteria, such as acceptable guidelines, Se hela listan på ifeat.org All data in this Table are available from RIFM and are listed in the RIFM Database. NOEL = No Observed Effect Level; HRIPT = Human Repeat Insult Patch Test; MAX = Human Maximization Test; LOEL = Lowest Observed Effect Level; NA = Not Available 1Data derived from HRIPT or Human Max tests 2Gerberick et al., 2001 2008-02-01 · The RIFM database can function as a focused literature search on fragrance ingredients in preparation for REACH registration. It was established in 1983 and through extensive research, testing and monitoring of literature, RIFM maintains the database as a comprehensive source of physical-chemical, toxicological and eco-toxico-logical data associated with known fragrance and flavor materials. The database is designed to support the FDA's post-marketing safety surveillance program for drug and therapeutic biologic products.